NEMBUTAL Sodium Solution (pentobarbital sodium injection) is a sterile solution for intravenous or intramuscular injection. Each mL contains pentobarbital sodium 50 mg, in a vehicle of propylene glycol, 40%, alcohol, 10% and water for injection, to volume. The pH is adjusted to approximately 9.5 with hydrochloric acid and/or sodium hydroxide.
Uses of Nembutal (Pentobarbital):
- It is used to treat sleep problems.
- It is used to calm you before a procedure.
- It is used to treat seizures.
- It is used to put you to sleep for surgery.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Nembutal (Pentobarbital)?
- If you have an allergy to pentobarbital or any other part of pentobarbital.
- If you are allergic to pentobarbital; any part of pentobarbital; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have ever had porphyria.
- If you have liver disease.
This is not a list of all drugs or health problems that interact with pentobarbital.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take pentobarbital with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
How is this medicine Nembutal (Pentobarbital) best taken?
Use pentobarbital as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a muscle or vein.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
How do I store and/or throw out Nembutal (Pentobarbital)?
- If you need to store pentobarbital at home, talk with your doctor, nurse, or pharmacist about how to store it.
What is the most important information I should know about Nembutal Sodium (Injectable)?
You should not use pentobarbital if you are allergic to it, or if you have:
- a history of porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).
Tell your doctor if you have ever had:
- liver disease;
- kidney disease;
- temporary or chronic pain; or
- an addiction to phenobarbital or similar medicines.
Pentobarbital may harm an unborn baby. If you use this medicine during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.
Phenobarbital can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.
Sedatives used during surgery may affect brain development in a young child or unborn baby (when used in the mother), leading to learning or behavior problems later in life. Long surgeries or repeated procedures pose the highest risks.
Ask a doctor if it is safe to breastfeed shortly after you receive pentobarbital.
What are the side effects of Nembutal Sodium (Injectable)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- confusion, agitation, hallucinations;
- weak or shallow breathing;
- slow heart rate, weak pulse; or
- a light-headed feeling, like you might pass out.
Side effects such as confusion, depression, or excitement may be more likely in older adults and those who are ill or debilitated.
Common side effects may include:
- drowsiness, dizziness;
- loss of balance or coordination;
- nausea, vomiting, constipation;
- overactive reflexes;
- sleep problems (insomnia), nightmares; or
- feeling restless or excited (especially in children or older adults).
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